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467876 trans-4-Hydroxy-lomustine CAS: 56239-24-8

Specifications
References
CAS Number
56239-24-8
Grade
Highly Purified
Molecular Formula
C9H16ClN3O3
Molecular Weight
249.69
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
1-(2-Chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitrosourea; NSC 239717; trans-4-Hydroxy CCNU

trans-4-Hydroxy-lomustine is an impurity of lomustine which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine.

Synonyms
1-(2-Chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitrosourea; NSC 239717; trans-4-Hydroxy CCNU
CAS No
56239-24-8
Molecular Formula
C9H16ClN3O3
Molecular Weight
249.69
Appearance
Light yellow solid
Purity
As reported
Melting Point
107-111°C
Solubility
Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Johnston, T.P., et al.: J. Med. Chem., 9, 892 (1966); Oliverio, V.T., et al.: Cancer Res., 30, 1330 (1970); Thompson, G.R., et al.: Toxicol. Appl. Pharmacol., 21, 405 (1972); Al-Shammary, F.J., et al.: Anal. Profiles Drug Subs., 19, 315 (1990)
USBio References
No references available
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