Epidermal growth factor receptor (EGFR) is a cell surface receptor often mutated in cancer cells. α-(5-Fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-N-2-thiazolyl-2H-isoindole-2-acetamide is an allosteric EGFR inhibitor that is selective against drug-resistant EGFR mutants.
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