USBio Logo

C7505-15B Cochlioquinone B CAS: 32450-26-3

Specifications
References
CAS Number
32450-26-3
Grade
Highly Purified
Molecular Formula
C28H40O6
Molecular Weight
472.61
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
+4°C

Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and a phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A that inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have been recently shown to be antagonists of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1).

Purity: >99% by HPLC
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Related to: Cochlioquinone A
Source
Bipolaris leersia
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Cochlioquinones and epi-cochlioquinones: antagonists of the human chemokine receptor CCR5 from |Bipolaris brizae and Stachybotrys chartarum. Yoganathan K. et al. J. Antibiot. 2004, 57, 59. |2. Cochlioquinone A1, a new anti-angiogenic agent from Bipolaris zeicola. Jung H.J. et al. Bioorg. Med. |Chem. 2003, 11, 4743. |3. Inhibitory activity of diacylglycerol acyltransferase by cochlioquinones A and A1. Lee H.B. et al. J. |Antibiot. 2003, 56, 967. |4. Phytotoxic compounds cochlioquinones are inhibitors of mitochondrial NADH-ubiquinone reductase. |Lim C.-H. et al. J. Pesticide Sci. 1996, 21, 213.
USBio References
No references available
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
  • Contact Us

    Visit our technical library or contact our support staff to answer your questions.

    Telephone:
    1-800-520-3011

    Library | Contact

    Distributors

    For customers outside of the United States, please use one of our many distributors.

    View Distributors

    Payment Methods

    We accept the following payment methods as well as pay-by-invoice.

    MasterCard Visa PayPal
    © 2023-2024 United States Biological - All Rights Reserved