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C7852-52 Conglobatin CAS: 72263-05-9

Specifications
References
CAS Number
72263-05-9
Grade
Highly Purified
Molecular Formula
C28H38N2O6
Molecular Weight
498.618
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Isolated from Streptomyces conglobatus, conglobatin has a unusual dimeric macrolide dilactone structure with pendant oxazole groups. It exhibited an IC50 of 0.63 ug/ml in a NFAT-dependent transcription assay. No toxicity was observed at doses up to 1000 mg/kg when administered to mice either orally or interperitoneally.

Purity: >95% by HPLC
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Related to: Elaiophyllin
Source
Streptomyces conglobatus
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Simple aromatics identified with a NFAT-lacZ transcription assay for the detection of |immunosuppressants. Burres N.E. et al. J. Antibiot. 1995, 48, 380. |2. Conglobatin, a novel macrolide dilactone from Streptomyces conglobatus ATCC 31005. Westley J.W. et |al. J. Antibiot. 1979, 32, 874.
USBio References
No references available
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