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M3547-32 O-Methylviridicatin (AIDS-089094, 3-Methoxy-4-phenyl-1H-quinolin-2-one) CAS: 6152-51-4

Specifications
References
CAS Number
6152-51-4
Grade
Highly Purified
Molecular Formula
C16H13NO2
Molecular Weight
251.3
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C/-20°C
AIDS-089094, 3-Methoxy-4-phenyl-1H-quinolin-2-one

3-O-Methylviridicatin is a metabolite produced by several species in the genus, Penicillium. Recently, 3-O-methylviridicatin was demonstrated to be a strong inhibitor of the tumor necrosis factor alpha (TNF)-induced replication of human immunodeficiency virus (HIV). Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite.

Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility
Source
Penicillium sp.
Purity
> 99% by HPLC
Form
White solid
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Studies in the biochemistry of microorganisms. 93. Cyclopenin, a nitrogen-containing metabolic product of Penicillium cyclopium Westling. Bracken A. et al. Biochem J. 1954, 57, 587. 2. Isolation of viridicatin from Penicillium palitans. J. Arch. Microbiol. 1970, 73, 261. 3. Isolation and characterization of the fungal metabolite 3-O-methylviridicatin as an inhibitor of tumour necrosis factor alpha-induced human immunodeficiency virus replication. Heguy A. et al. Antivir. Chem. Chemother. 1998, 9, 149.
USBio References
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