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V1021 Valinomycin CAS: 2001-95-8

Specifications
References
CAS Number
2001-95-8
Grade
Highly Purified
MDL Number
MFCD00005114
Molecular Formula
C54H90N6O18
Molecular Weight
1111.32
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone; 1Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-|hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl); NSC 122023

Valinomycin is a hydrophobic cyclodepsipeptide with potent antitumor activity. Valinomycin is a highly selective potassium ionophore and this action leads to a diverse range of profound cell membrane effects. More recently, Valinomycin has found application in biosensors.

Synonyms
3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone; 1Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α- hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl); NSC 122023
CAS No
2001-95-8
Molecular Formula
C54H90N6O18
Molecular Weight
1111.32
Purity (HPLC)
≥95%
Appearance
White to beige powder to crystalline powder
Melting Point
188-189°C (lit)
Specific Optical Rotation [alpha]D (c=1, benzene)
30.0-34.0º
FT-IR Spectrum
Conforms to spectrum
Storage and Stability
Store at -20ºC. Product is stable for 12 months after receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. K+-selective nanospheres: maximising response range and minimising response time. Ruedas-Rama M.J. & Hall E.A. Analyst. 2006, 131, 1282. 2. Potentiometric combination ion/carbon dioxide sensors for in vitro and in vivo blood measurements. 3. Collison M.E. el al. Anal. Chem. 1989, 61, 2365. 4. Ivanov, et al., Biochem. Biophys. Res. Commun., 34, 803 (1969); Duax, et al., Science, 176, 911 (1972)
USBio References
No references available
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