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143955 LOX-1/OLR1 BioAssay™ ELISA Kit, Mouse

Specifications
References
Brand
BioAssay™
Gene ID
108078
Kit Type
Sandwich ELISA
Tests
96
Sensitivity
< 1 pg/ml
Detection Method
Colorimetric
Detection Range
31.2pg/ml-2000pg/ml
Sample Matrix
cell culture supernates, serum and plasma (heparin, EDTA)
EU Commodity Code
38220000
UN DOT Shipping
UN2796 PGII
Shipping Temp
Blue Ice
Storage Temp
4°C/-20°C

Sandwich ELISA quantitative detection kit for Mouse LOX-1 in cell culture supernates, serum and plasma (heparin, EDTA).

Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the OLR1 gene. It belongs to the C-type lectin superfamily. The LOX1 gene is mapped to to 12p13-p12. The protein has got the amino acids of 363. It can be detected in various tissues, highly expressed in placenta. This protein may be involved in the regulation of Fas-induced apoptosis and play a role as a scavenger receptor. The standards of this kit are recombinant mouse LOX-1 (R60-I363), with molecular weight of 36.3kD.
Assay Range
31.2pg/ml-2000pg/ml
Sensitivity
< 1 pg/ml
Crossreactivity
There is no detectable cross-reactivity with other relevant proteins.
Uniprot ID
Q9EQ09
Entrez Gene ID
108078
Kit Components
96-well plate pre-coated with anti-LOX-1/OLR1, Mouse Lyophilized recombinant LOX-1/OLR1, Mouse standard, 10ng/tube, 2Ea USB Cat No Kit Component 143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution) 143697 Sample diluent buffer, 30ml 143698 Antibody diluent buffer, 12ml 143699 ABC diluent buffer, 12ml 143700 TMB color developing agent, 10ml 143701 TMB stop solution, 10ml
Storage and Handling
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
References
1. Li X, Bouzyk MM, Wang X (Nov 1998). "Assignment of the human oxidized low-density lipoprotein receptor gene (OLR1) to chromosome 12p13.1-p12.3, and identification of a polymorphic CA-repeat marker in the OLR1 gene". Cytogenet Cell Genet 82 (1-2): 34–6. doi:10.1159/000015059. PMID 9763655.|2. Honjo, M., Sawamura, T., Hinagata, J., Nakamura, K., Sanada, N., Tanihara, H., Honda, Y., Kiryu, J. Expression of LOX-1, an oxidized low-density lipoprotein receptor, in choroidal neovascularization. Arch. Ophthal. 122: 1873-1876, 2004. [PubMed: 15596594]|
USBio References
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