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374538 OLIG2, Recombinant, Human, aa1-323, His-SUMO-Tag (Oligodendrocyte Transcription Factor 2) CAS:

Specifications
References
Grade
Purified
Swiss Prot
Q13516
Molecular Weight
48.4
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C
Class B basic helix-loop-helix protein 1, bHLHb1 Class E basic helix-loop-helix protein 19, bHLHe19 Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17

Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.

Source
Recombinant protein corresponding to aa1-323 from human OLIG2, fused to His-SUMO-Tag at N-terminal, expressed in E. coli.
Molecular Weight
~48.4kD
Amino Acid Sequence
MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
As Reported
Form
Supplied as a liquid in Tris, 50% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. "Protein kinase C-binding protein." Kuroda S., Tokunaga C., Kiyohara Y., Konishi H., Kikkawa U.Submitted (FEB-1996).
USBio References
No references available
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