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374722 Pla2g12a, Recombinant, Mouse, aa26-192, His-SUMO-Tag (Group XIIA Secretory Phospholipase A2) CAS:

Specifications
References
Grade
Purified
Swiss Prot
Q9EPR2
Molecular Weight
34.7
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C
Phosphatidylcholine 2-acylhydrolase 12A

PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.

Source
Recombinant protein corresponding to aa26-192 from mouse PLA2G12A, fused to His-SUMO-Tag at N-terminal, expressed in E. coli.
Molecular Weight
~34.7kD
Amino Acid Sequence
QEQDQTTDWRATLKTIRNGIHKIDTYLNAALDLLGGEDGLCQYKCSDGSKPVPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICRDVQKTLGLSQNVQACETTVELLFDSVIHLGCKPYLDSQRAACWCRYEEKTDL
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
As Reported
Form
Supplied as a liquid in Tris, 50% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells. Ho I.C., Arm J.P., Bingham C.O. III, Choi A., Austen K.F., Glimcher L.H.J. Biol. Chem. 276:18321-18326(2001).
USBio References
No references available
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