SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination
| Product | Size | List | Your Price | Qty | Ext Price | ||||
|---|---|---|---|---|---|---|---|---|---|
| Subtotal: | Subtotal: | ||||||||
| Subtotal: | Subtotal: | ||||||||
| Total Coupon Savings: | Total Coupon Savings: | () | |||||||
| Your cart is currently empty. | |||||||||
| - Coupon Code | |||||||||
We accept the following payment methods as well as pay-by-invoice.
TDS
NCBI
UniProt
Tech Support
Customer Service
