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375286 SFTPB, Recombinant, Bovine, aa188-266, His-Tag (Pulmonary Surfactant-Associated Protein B) CAS:

Specifications
References
Grade
Purified
Swiss Prot
P15781
Molecular Weight
10.7
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C
6kD protein, Pulmonary surfactant-associated proteolipid SPL(Phe)

Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.

Full length recombinant protein corresponding to aa188-266 from bovine SFTPB, fused to 6X His-B2M-Tag at N-terminal, expressed in Yeast. Accession/Uniprot: P15781
Molecular Weight
~10.7kD
Amino Acid Sequence
FPIPIPYCWLCRTLIKRIQAVIPKGVLAMTVAQVCHVVPLLVGGICQCLVERYSVILLDTLLGRMLPQLVCGLVLRCSS
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, Yeast
Purity
≥85% (SDS-PAGE)
Concentration
As Reported
Form
Supplied as a liquid in Tris, 50% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Characterization of bovine surfactant proteins B and C by electrospray ionization mass spectrometry. Liu S., Zhao L., Manzanares D., Doherty-Kirby A., Zhang C., Possmayer F., Lajoie G.A.Rapid Commun. Mass Spectrom. 22:197-203(2008).
USBio References
No references available
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